Xpert Ultra Assay on Stool to Diagnose Pulmonary Tuberculosis in Children
نویسندگان
چکیده
منابع مشابه
Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.
متن کاملXpert(®) MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children.
SETTING A tertiary care teaching hospital in New Delhi, India. OBJECTIVE To determine the sensitivity and specificity of the Xpert(®) MTB/RIF assay in paediatric pulmonary tuberculosis (PTB) using MGIT™ culture as gold standard. METHODS After ethical approval had been obtained, 50 patients aged 0-14 years with suspected PTB were enrolled. Sputum/induced sputum and gastric lavage from the pa...
متن کاملUse of string test and stool specimens to diagnose pulmonary tuberculosis☆
BACKGROUND The Xpert MTB/RIF (MTB/RIF) test has advanced the field of tuberculosis (TB) diagnostics; however, depending on age and HIV status, 10-85% of individuals with presumed pulmonary TB (PTB) are unable to produce sputum. METHODS The feasibility of using MTB/RIF and culture on stool and string test specimens from 13 adult patients with presumed PTB was studied. RESULTS The string test...
متن کاملurine pcr evaluation to diagnose pulmonary tuberculosis
conclusions with regard to the ease of urine sample preparation and the 100% specificity the pcr method, performing urine pcr could be used as a diagnostic aid in ptb cases obtaining sputum samples is problematic. results results of the current study indicated that 48 (62.3%) patients out of 77 had a positive sputum culture. urine cultures and acid-fast smears were negative. urine pcr-tb was po...
متن کاملStool Culture for Diagnosis of Pulmonary Tuberculosis in Children
Bacteriological confirmation of Mycobacterium tuberculosis is achieved in the minority of young children with tuberculosis (TB), since specimen collection is resource intensive and respiratory secretions are mostly paucibacillary, leading to limited sensitivity of available diagnostic tests. Although molecular tests are increasingly available globally, mycobacterial culture remains the gold sta...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2020
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciaa583